Detalle Publicación

Successful Colon Cancer Eradication after Chemoimmunotherapy Is Associated with Profound Phenotypic Change of Intratumoral Myeloid Cells

Título de la revista: JOURNAL OF IMMUNOLOGY
ISSN: 0022-1767
Volumen: 186
Número: 2
Páginas: 807 - 815
Fecha de publicación: 2011
IL-12 is a potent immunostimulatory cytokine, but its impact as an antitumor drug in clinical practice is limited. Upsurge of regulatory T cells (Treg) in the tumor milieu has been proposed to limit the efficacy of the treatment.