Detalle Publicación

ARTÍCULO
Thymidylate synthase polymorphisms in genomic DNA as clinical outcome predictors in a European population of advanced non-small cell lung cancer patients receiving pemetrexed
Título de la revista: JOURNAL OF TRANSLATIONAL MEDICINE
ISSN: 1479-5876
Volumen: 12
Páginas: 98
Fecha de publicación: 2014
Resumen:
In our series, 3R/3R polymorphism correlated with a superior OS. Also, this polymorphism, when associated to wild type EGFR, was related to a higher ORR to pemetrexed. Toxicity was not significantly correlated with a specific TS genotype.