Detalle Publicación

Acellular vaccines for ovine brucellosis: a safer alternative against a worldwide disease

Título de la revista: EXPERT REVIEW OF VACCINES
ISSN: 1476-0584
Volumen: 11
Número: 1
Páginas: 87 - 95
Fecha de publicación: 2012
Ovine brucellosis is a very contagious zoonotic disease distributed worldwide and constitutes a very important zoosanitary and economic problem. The control of the disease includes animal vaccination and slaughter of infected flocks. However, the commercially available vaccine in most countries is based on the attenuated strain Brucella melitensis Rev 1, which presents important safety drawbacks. This review is focused on the most recent and promising acellular vaccine proposals.