Resumen:
The main goal of the present work is to investigate the modulatory effect of Brassica oleracea italica x alboglabra (Bimi (R)) on gut microbiota composition through an in vitro digester and an in vivo trial. The digester simulates the entire gastrointestinal digestive process. The maintenance of the microbial population during the stabilization and treatment period was checked by bacteria plate counts The human trial included 15 Spanish adults who included 90 g of Bimi (R) every two days into their habitual diet. Plate counts showed that the treatment with Bimi (R) elicits eubiosis, favouring the growth of health promoting gut microbes, as seen on the total anaerobic values In vitro results showed many short chain fatty acids (SCFAs)-producing bacteria favoured by synergetic effects of the fibres, resistant starch and polyphenols present in Bimi (R). The human intervention confirmed some of these results and evidenced an increase in beneficial bacteria such as the genus Lactobacillus, and the species Chistensenella minuta, and Ruminococcus bromii, suggesting that Bimi (R) is capable of modulating gut microbiota towards a healthier status, with great potential in the management of human disorders related to microbiota dysbiosis.
