Detalle Publicación

EDITORIAL

Senescent T cells as a resistance mechanism to lung cancer immunotherapy

Autores: Salas Benito, Diego; Eguren Santamaría, Iñaki; Fernández de Sanmamed Gutiérrez, Miguel (Autor de correspondencia)
Título de la revista: CLINICAL CANCER RESEARCH
ISSN: 1078-0432
Volumen: 27
Número: 2
Páginas: 374 - 376
Fecha de publicación: 2021
Resumen:
It has been reported that a group of patients with advanced non- small cell lung cancer showed circulating T cells with a senescent phenotype, and an abundance of such cells is associated with worse clinical response to immune checkpoint inhibitors. This study encourages further analysis of the role of senescent T cells in resistance to lung cancer immunotherapy.
DOI: https://doi.org/10.1158/1078-0432.CCR-20-3507
Impacto:
Google Scholar