Detalle Publicación

ARTÍCULO
Fungal biofilms: from bench to bedside
Título de la revista: REVISTA ESPAÑOLA DE QUIMIOTERAPIA
ISSN: 0214-3429
Volumen: 31
Número: Supl. 1
Páginas: 35 - 38
Fecha de publicación: 2018
Resumen:
Biofilms cause recurrent invasive infections that are difficult to eradicate because of their high resistance to antimicrobials and host defence mechanisms. Fungal biofilm-related infections are associated with high mortality rates. Although current guidelines recommend catheter removal for catheter-related bloodstream infections due to Candida species, several studies have shown that the efficacy of the antifungal lock technique. The use of combinations of antifungal agents may improve the management of biofilm-related fungal infections and prevent the emergence of resistance associated with monotherapy. Since the presence of mixed bacterial-fungal biofilm infections is very prevalent, a combination of antibacterial and antifungal agents should be considered.