Detalle Publicación

ARTÍCULO
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
Autores: Caers, J. (Autor de correspondencia); Paiva, Bruno; Zamagni, E.; Leleu, X.; Blade, J. ; Kristinsson, S. Y.; Touzeau, C.; Abildgaard, N.; Terpos, E. ; Heusschen, R.; Ocio, E.; Delforge, M. ; Sezer, O. ; Beksac, M.; Ludwig, H. ; Merlini, G.; Moreau, P. ; Zweegman, S. ; Engelhardt, M.; Rosinol, L.
Título de la revista: JOURNAL OF HEMATOLOGY AND ONCOLOGY
ISSN: 1756-8722
Volumen: 11
Número: 1
Páginas: 10
Fecha de publicación: 2018
Lugar: WOS
Resumen:
Solitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or intraosseous. In some patients, a bone marrow aspiration can detect a low monoclonal plasma cell infiltration which indicates a high risk of early progression to an overt myeloma disease. Before treatment initiation, whole body positron emission tomography-computed tomography or magnetic resonance imaging should be performed to exclude the presence of additional malignant lesions. For decades, treatment has been based on high-dose radiation, but studies exploring the potential benefit of systemic therapies for high-risk patients are urgently needed. In this review, a panel of expert European hematologists updates the recommendations on the diagnosis and management of patients with solitary plasmacytoma.