Detalle Publicación

ARTÍCULO
Thermal behavior of quinoxaline 1,4-di-N-oxide derivatives
Título de la revista: JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
ISSN: 1388-6150
Volumen: 127
Número: 2
Páginas: 1655 - 1661
Fecha de publicación: 2017
Lugar: WOS
Resumen:
The thermal hazard of a series of quinoxaline 1,4-di-N-oxide derivatives, designed to act as prodrugs, whose chemical structure undergoes a very rapid decomposition, has been evaluated. The fusion and thermal decomposition of the compounds have been studied by thermogravimetry, differential scanning calorimetry, and mass spectrometry (MS-DIP). The results obtained indicate that the decomposition process from the loss of one of the oxygens linked to a nitrogen of the quinoxaline involves the release of a large quantity of vapor in a very small time interval. The enthalpy is higher than 300 J g(-1); in some cases, it is around 1000 J g(-1).