A highly nonlinear model of the energy flow in a magneto-sensitive (MS) vibration isolation system is developed where it is possible to investigate the influences of MS rubber material parameters; magnetic field strength; MS isolator dimension and position; excitation force magnitude, position and frequency; engine mass, inertia and dimension and, finally, foundation inertance. The MS vibration isolation system consists of an engine modelled by a solid mass, excited by a vertical force and mounted upon four MS isolators being connected to a relatively stiff foundation characterised by its driving-point and transfer inertances at and between the connection points. The energy flow into the foundation is the most appropriate indicator of the effectiveness of a real vibration isolation system while considering both foundation velocity and force. The MS isolator model applied is a nonlinear MS rubber model including frequency, dynamic amplitude and magnetic field dependence. The energy flow model results are compared to those of measurements, showing good agreement. Finally, parameter studies are carried out. The developed energy flow model provides a basis for designing MS vibration isolation systems to meet specific requirements. (C) 2013 Elsevier Ltd. All rights reserved.