Detalle Publicación

Impact of initial FDG PET/CT in the management plan of patients with locally advanced head and neck cancer

Autores: Arias, F; Chicata, V; García Velloso, María José; Asin, G; Uzcanga, M; Eito, C; Quilez, I; Viudez, A; Saenz, J; Hernandez, I; Caicedo, C; Errasti, M; Barrado, M; Garcia-Bragado, M
ISSN: 1645-9725
Volumen: 17
Número: 2
Páginas: 139-144
Fecha de publicación: 2015
To determine the impact of initial FDG PET/CT staging on clinical stage and the management plan in patients with locally advanced head and neck cancer (LAHNC). We retrospectively reviewed the records of 72 consecutive patients (2007-2010) staged with PET/CT and conventional CT with tumours of hypopharynx/larynx (26 patients, 36 %), oral cavity (17 patients, 24 %), oropharynx (16 patients, 22 %), nasopharynx (12 patients, 17 %), and others (2 %). The impact of PET/CT on management plans was considered high when PET/CT changed the planned treatment modality or treatment intent, and intramodality changes were considered as minor changes with low impact. FDG PET/CT changed the stage in 27 patients and had high impact on the management plan in 12 % of patients (detection of distant metastases in 6 patients and stage II in 2 patients). Intramodality changes were more frequent: FDG PET/CT altered the TNM stage in 18/72 (25 %) of patients, upstaging N stage in 90 % of patients with low impact. Initial FDG PET/CT staging not only improves stage but also affects the management plan in LAHNC patients.