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Neovascularization potential of blood outgrowth endothelial cells from patients with stable ischemic heart failure is preserved

Autores: Dauwe, D.; Pelacho Samper, Beatriz; Wibowo, A.; Walravens, A. S.; Verdonck, K.; Gillijns, H. ; Caluwe, E.; Pokreisz, P.; van Gastel, N.; Carmeliet, G.; Depypere, M.; Maes, F.; Driessche, N. V. ; Droogne, W.; Van Cleemput, J. ; Vanhaecke, J. ; Prosper Cardoso, Felipe; Verfaillie, C. M.; Luttun, A.; Janssens, S.
Título de la revista: AMERICAN HEART ASSOCIATION. JOURNAL. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE
ISSN: 2047-9980
Volumen: 5
Número: 4
Páginas: e002288
Fecha de publicación: 2016
Resumen:
BOECs can be successfully culture-expanded from patients with ICMP. In contrast to impaired functionality of ICMP-derived bone marrow MNCs, BOECs retain a robust proangiogenic profile, both in vitro and in vivo, with therapeutic potential for targeting ischemic disease.
DOI: https://doi.org/10.1161/JAHA.115.002288.
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