Detalle Publicación


Effectiveness of the trivalent influenza vaccine in Navarre, Spain, 2010-2011: a population-based test-negative case-control study

Autores: Martínez-Baz, I; Martínez-Artola, V.; Reina González, Gabriel; Guevara, M.; García Cenoz, Manuel Fermín; Morán, J.; Irisarri, F.; Arriazu, M.; Albéniz, E.; Castilla, J.
Título de la revista: BMC PUBLIC HEALTH
ISSN: 1471-2458
Volumen: 13
Páginas: 191
Fecha de publicación: 2013
The 303 confirmed influenza cases (88% for A(H1N1)pdm09 influenza) were compared with the 286 influenza test-negative controls. The percentage of persons vaccinated against influenza was 4.3% and 15.7%, respectively (p<0.001). The adjusted estimate of effectiveness was 67% (95% CI: 24%, 86%) for all patients and 64% (95% CI: 8%, 86%) in those with an indication for vaccination (persons age 60 or older or with major chronic conditions). Having received both the 2010-2011 seasonal influenza vaccine and the 2009-2010 pandemic influenza vaccine provided 87% protection (95% CI: 30%, 98%) as compared to those not vaccinated. CONCLUSION: The 2010-2011 seasonal influenza vaccine had a moderate protective effect in preventing laboratory-confirmed influenza.