Detalle Publicación


Dietary total antioxidant capacity is negatively associated with some metabolic syndrome features in healthy young adults

Autores: Puchau de Lecea, María Blanca; Zulet Alzórriz, María de los Ángeles; Gonzalez de Echavarri, A; Miranda Hermsdorff, Helen Hermana; Martínez Hernández, Alfredo
Título de la revista: Nutrition
ISSN: 0899-9007
Volumen: 26
Número: 5
Páginas: 534 - 541
Fecha de publicación: 2010
Objective: Oxidative stress has been related to the development of obesity and other features accompanying chronic diseases Furthermore, dietary antioxidant intake has been suggested to protect against oxidative damage and related clinical complications Therefore, the aim of this study was to assess the potential associations among dietary total antioxidant capacity (TAC) and several early metabolic syndrome manifestations in healthy young adults. Methods: Anthropometric variables and blood pressure from 153 healthy subjects (20 8 +/- 27 y old) were measured Dietary intake was assessed by a validated food-frequency questionnaire and a 3-d record, which were also used to calculate TAC and to adjust by daily energy intake. Fasting blood samples were collected for measuring biochemical markers. Results: Dietary TAC showed positive and significant associations with fiber, folic acid, vitamin A and C. magnesium, selenium, and zinc intakes, after adjusting by sex and daily energy intake Interestingly, systolic blood pressure, serum glucose. and free fatty acids were also found to be negatively associated with dietary TAC independently of sex and daily energy intake Also, a relevant relation was found between body mass index and TAC values. Interestingly, after adjusting by sex and daily enemy intake, complement factor-3 circulating levels appeared to be negatively and significantly associated with dietary TAC, whereas blood plasminogen activator inhibitor-1 and homocysteine concentrations showed an Inverse marginally statistical trend. Conclusions: These data suggest that dietary TAC may be also a potential early estimate of the risk to develop metabolic syndrome features and that dietary TAC could be a useful research tool in assessing antioxidant intake