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Improving disease control in advanced colorectal cancer: panitumumab and cetuximab.

Autores: Rodríguez Rodríguez, J.; Viudez Berral, Antonio; Ponz Sarvisé, M.; Gil Aldea, Isabel; Chopitea, A.; García-Foncillas López, Jesús Miguel; Gil Bazo, Ignacio
Título de la revista: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
ISSN: 1040-8428
Volumen: 74
Número: 3
Páginas: 193 - 202
Fecha de publicación: 2010
Resumen:
One of the last available drugs for the management of advanced colorectal cancer is panitumumab, a well-tolerated and effective anti-EGFR monoclonal antibody approved as a single agent in chemotherapy refractory patients. We discuss the current evidence supporting panitumumab for metastatic colorectal cancer treatment, potential predictive biomarkers and ongoing clinical trials with different combinations including panitumumab
DOI: https://doi.org/10.1016/j.critrevonc.2009.07.005
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