Resumen: New innovative methodologies in simulation are transforming healthcare education while promoting patient safety and improving outcomes. The decision to use simulation to achieve certain outcomes is based on a needs assessment, specific learning objectives and KSA (Knowledge, Skills and Attitudes). The Standards of Best Practice¿ developed by INACSL guide the development of simulation-based experiences. This work is the first to offer recommendations on how to use simulation as an effective educational tool based on current evidence and best practice. This association along with the Association for Simulated Practice in Healthcare (ASPiH) emphasizes the role of debriefing as an essential component of the simulation methodology. Additionally, the preparation of the simulation-based experience requires defined learning objectives in addition to a quality prebrief. Moving forward, we will witness the inclusion of more virtual, augmented reality simulations to augment traditional clinicals.