Detalle Publicación

Spanish consensus for the management of patients with anaplastic cell thyroid carcinoma

Autores: Jiménez-Fonseca, P.; Gómez Sáez, J. M.; Santamaría Sándi, J.; Capdevila, J.; Navarro González, E.; Zafon Llopis, C.; Ramon y Cajal Asensio, T.; Riesco-Eizaguirre, G.; Grande, E.; Galofre Ferrater, Juan Carlos
Título de la revista: CLINICAL AND TRANSLATIONAL ONCOLOGY
ISSN: 1699-048X
Volumen: 19
Número: 1
Páginas: 12 - 20
Fecha de publicación: 2017
Resumen:
Anaplastic thyroid cancer (ATC) is the most aggressive solid tumor and almost uniformly lethal in humans. The Boards of the Thyroid Cancer Group of the Spanish Society of Endocrinology and Nutrition and the Grupo Espaol de Enfermedades Hu,rfanas e Infrecuentes of the Spanish Society of Oncology requested that an independent task force draft a more comprehensive consensus statement regarding ATC. All relevant literature was reviewed, including serial PubMed searches together with additional articles. This is the first, comprehensive Spanish consensus statement for ATC and includes the characteristics, diagnosis, initial evaluation, treatment goals, recommendations and modalities for locoregional and advanced disease, palliative care options, surveillance, and long-term monitoring. Newer systemic therapies are being investigated, but more effective combinations are needed to improve patient outcomes. Though more aggressive radiotherapy has reduced locoregional recurrences, median overall survival has not improved in more than 50 years.