Detalle Publicación


Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study.

Autores: Caronia, D.; Patiño García, Ana; Pérez-Martínez, A.; Pita, G.; Moreno, L.T.; Zalacain Díez, Marta; Molina, B.; Colmenero, I.; Sierrasesúmaga Ariznavarreta, Luis; Benitez, J.; González-Neira, A.
Título de la revista: PLOS ONE
ISSN: 1932-6203
Volumen: 6
Número: 10
Páginas: e26091
Fecha de publicación: 2011
Our findings suggest that these polymorphisms may affect osteosarcoma treatment efficacy. If these associations are independently validated, these variants could be used as genetic predictors of clinical outcome in the treatment of osteosarcoma, helping in the design of individualized therapy.