Detalle Publicación


Noninvasive renal perfusion measurement using Arterial Spin Labeling (ASL) MRI: Basic concept

Libro: Preclinical MRI of the Kidney: Methods and Protocols
Autores: Ku, M. C.; Fernández Seara, María Asunción; Kober, F.; Niendorf, T.
Lugar de Edición: New York
Editorial: Springer
Fecha de publicación: 2021
Página Inicial - Final: 229 - 239
ISBN: 978-1-0716-0978-1
Resumen: The kidney is a complex organ involved in the excretion of metabolic products as well as the regulation of body fluids, osmolarity, and homeostatic status. These functions are influenced in large part by alterations in the regional distribution of blood flow between the renal cortex and medulla. Renal perfusion is therefore a key determinant of glomerular filtration. Therefore the quantification of regional renal perfusion could provide important insights into renal function and renal (patho)physiology. Arterial spin labeling (ASL) based perfusion MRI techniques, can offer a noninvasive and reproducible way of measuring renal perfusion in animal models. This chapter addresses the basic concept of ASL-MRI.