Detalle Publicación

The Long Neglected Player: Modeling Tumor Uptake to Guide Optimal Dosing

Título de la revista: CLINICAL CANCER RESEARCH
ISSN: 1078-0432
Volumen: 24
Número: 14
Páginas: 3236 - 3238
Fecha de publicación: 2018
Pharmacokinetic modeling, traditionally using drug exposure, is widely used to support decision-making in translational medicine and patient care. The development of mechanistic computational models that integrate drug concentrations at the site of action making use of existing knowledge opens a new paradigm in optimal dosing. (C) 2018 AACR.