Detalle Publicación

A "Counter-Enhancer'' in Tumor Suppression

Título de la revista: CELL
ISSN: 0092-8674
Volumen: 173
Número: 6
Páginas: 1318 - 1319
Fecha de publicación: 2018
The role of the noncoding genome in cancer biology is continually expanding. Cho et al. reveal a new and unexpected mechanism for the regulation of MYC expression mediated by the promoter sequence of its neighbor gene PVT1. This DNA element acts as a promoter-enhancer competitor and a candidate tumor suppressor.'