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Publicaciones científicas más recientes (desde 2010)

Autores: Erhard, Álvaro Armin; Quincoces, Gemma; et al.
Revista: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
ISSN 1619-7070  Vol. 46  Nº SUPPL 1  2019  págs. S316 - S316
Autores: Rúa, Marta; Collantes M; et al.
Revista: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
ISSN 1619-7070  Vol. 46  Nº SUPPL 1  2019  págs. S316 - S316
Autores: Carmona, Francisco de Asís; Rúa, Marta; del Pozo, José Luis;
Revista: REVISTA ESPAÑOLA DE QUIMIOTERAPIA
ISSN 0214-3429  Vol. 30  Nº Supl 1  2017  págs. 42-47
Autores: Carmona, Francisco de Asís; Rúa, Marta; del Pozo, José Luis, (Autor de correspondencia)
Revista: REVISTA ESPAÑOLA DE QUIMIOTERAPIA
ISSN 0214-3429  Vol. 30  Nº Supl. 1  2017  págs. 42 - 47
In the last few years there has been an increase of implantable cardiac electronic device and vascular graft related infections. This is due in part to a higher complexity of some of these procedures and an increase in patient's comorbidities. Despite wide diagnosis methods availability, early stage diagnosis usually constitutes a challenge as often patients only denote insidious symptoms. In most confirmed cases, removal of the infected device is required to resolve the infection. This is mostly explainable because of bacterial ability to grow as biofilms on biomaterial surfaces, conferring them antimicrobial resistance. If removal is not possible, chronic suppressive antimicrobial therapy could be an option.
Autores: Carmona, Francisco de Asís; Torrellas,B.; Rúa, Marta; et al.
Revista: LANCET INFECTIOUS DISEASES
ISSN 1473-3099  Vol. 17  Nº 5  2017  págs. 477-478
Autores: Carmona, Francisco de Asís; Rúa, Marta; del Pozo, José Luis;
Revista: REVISTA ESPAÑOLA DE QUIMIOTERAPIA
ISSN 0214-3429  Nº Supl.1  2016  págs. 15-20
Infections caused by Staphylococcus aureus have had classically an important impact in morbidity and mortality in the nosocomial and community scene. The description of methicillin resistance among nosocomial isolates of S. aureus and his widespread diffusion has become methicillin-resistant S. aureus (MRSA) in one of the most common causes of bacterial nosocomial infections. In the last years MRSA strains have also emergence in the community. This together with a progressive increase in resistance to antibiotics used classically has become vancomycin in the treatment of choice in most cases according to clinical guidelines. As a result, a progressive rise in the minimum inhibitory concentration (MIC) to vancomycin has been reported. In this context strains with intermediate susceptibility to vancomycin (MIC 8-4 mg/L) and heteroresistance have been noted. These strains are associated with a higher risk of treatment failure when using vancomycin. Among isolates of S. aureus susceptible to vancomycin there has been described stains with elevated MICs (¿1.5 mg/L). It is controversial if the presence of these strains has an impact on clinical outcome if treatment with vancomycin or ß-lactams is prescribed. The development of new antibiotics with activity against MRSA and exploring synergies offer a promising alternative to treatment with vancomycin.