Revistas
Revista:
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
ISSN:
1860-5397
Año:
2023
Vol.:
19
Págs.:
78 - 88
Cyclodextrins, cyclic oligosaccharides with a hydrophobic cavity that form inclusion complexes with nonpolar molecules, can be used to functionalize other polysaccharides. Xanthan gum, locust bean gum or chitosan can be crosslinked using citric acid in the presence of ß-cyclodextrin to produce insoluble matrices. In this work, polymeric foams based on those polysaccharides and saponin have been prepared using a green synthesis method to increase the porosity of the matrices. The saponin of soapbark (Quillaja saponaria) has been used to obtain foams using different procedures. The influence of the synthesis path on the porosity of the materials and their corresponding sorption capacities in the aqueous phase were evaluated.
Revista:
CARBOHYDRATE POLYMERS
ISSN:
0144-8617
Año:
2022
Vol.:
288
Págs.:
119387
Polysaccharides such as xanthan, locust bean gum or chitosan are easily crosslinked and purified using citric acid in an ecofriendly process. In order to achieve an improved sorption capability towards hydrophobic solutes, B-cyclodextrin, a cyclic oligosaccharide, and lignin, a natural aromatic polymer, are incorporated in the same process. Once crosslinked, the influence of these on the sorption capacities towards model solutes has been assessed by comparing the sorption isotherms of matrices with or without the hydrophobic modifications. The sorption capacities of these materials for different phenolic compounds have also been tested to ascertain their efficiencies as a function of their affinities to B-cyclodextrin cavities and/or their partition coefficients. In addition, these functionalized carbohydrate matrices were successfully characterized by principal component analysis, which is a useful tool to select the most appropriate polymers to interact with a specific molecule.
Revista:
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN:
0141-8130
Año:
2021
Vol.:
180
Págs.:
570 - 577
Three different polysaccharides, xanthan gum, chitosan and locust bean gum, were crosslinked with or without ß-cyclodextrin, using citric acid in different ratios, to create "green" hydrogel matrices. The crosslinking of these polysaccharides was produced through an inexpensive and innocuous solvent-free synthesis process. A favorable swelling behavior of the hydrophilic matrices facilitates the sorption of the solutes tested. Interestingly, the amount of ß-cyclodextrin groups is not the only factor to yield the best sorption capability for hydrophobic model molecules: polysaccharides themselves also influence the sorption depending on their characteristic functional groups, the conformation of their chains and, as mentioned above, their degrees of swelling. In order to ascertain the effect of the polysaccharides on the sorption capabilities of a model sorbate (1-naphthol), isotherms using a wide range of solute concentrations were analyzed, and the Hill equation yielded the best fitting results and provided some insight into the mechanisms of interaction.
Revista:
GELS
ISSN:
2310-2861
Año:
2020
Vol.:
6
N°:
4
Págs.:
51
The incorporation of cyclodextrins into polymeric crosslinked gels of hydrophilic nature can be useful for promoting the sorption of hydrophobic molecules and/or modulating the release of active principles. The covalent addition of these excipients to the matrix integrates their solubilizing effect that can contribute to increase the capacity of retention of hydrophobic substances. In this study, three diverse polysaccharides, chitosan, xanthan gum, and locust bean gum, were crosslinked with or without beta-cyclodextrin, using citric acid in different ratios, to create hydrogel matrices. Through a green synthetic path, the efficient production of soluble and insoluble (hydrogel) networks functionalized with beta-cyclodextrin was achieved by means of a solventless procedure. The characterization of their chemical composition, swelling in water, and their sorption and release behavior were also carried out in this work.
Otros (PIUNA, fundaciones, contratos…)
Título:
Aplicaciones de matrices poliméricas de ciclodextrinas sintetizadas mediante procesos sostenibles
Código de expediente:
2018-15
Financiador:
UNIVERSIDAD DE NAVARRA
Convocatoria:
2020 Convocatoria PIUNA
Fecha de inicio:
01/09/2018
Fecha fin:
31/08/2021
Importe concedido:
4.170,00€