The political communities of western Asia Minor produced an enormous amount of inscriptions under Roman rule. For the period between AD 260 and 280, however, the epigraphic habit falls dramatically and this situation largely continues in the 4th and 5th centuries. The aim of this paper is to analyse the phenomenon in the transitional Tetrarchic age, when a notable increase in testimony, particularly milestones and texts related to the new regime (e.g. 'Edict of Prices'), can be observed. My study of continuities and changes concludes that the propagandistic efforts under the Tetrarchs did not ultimately coincide with a full reactivation of civic epigraphic culture and this new scenario should remain fundamental for our assessment of Late Antiquity in the region.