Detalle Publicación

ARTÍCULO
Obesity and COVID-19: A Perspective from the European Association for the Study of Obesity on Immunological Perturbations, Therapeutic Challenges, and Opportunities in Obesity
Autores: Goossens, G. H. (Autor de correspondencia); Dicker, D. ; Farpour-Lambert, N. J.; Fruhbeck Martínez, Gema; Mullerova, D. ; Woodward, E. ; Holm, J. C.
Título de la revista: OBESITY FACTS
ISSN: 1662-4025
Volumen: 13
Número: 4
Páginas: 439 - 452
Fecha de publicación: 2020
Lugar: WOS
Resumen:
Accumulating evidence suggests that obesity is a major risk factor for the initiation, progression, and outcomes of coronavirus disease 2019 (COVID-19). The European Association for the Study of Obesity (EASO), as a scientific and medical society dedicated to the promotion of health and well-being, is greatly concerned about the concomitant obesity and COVID-19 pandemics and their impact on health and society at large. In this perspective, we will address the inherent immunological perturbations and alterations in the renin-angiotensin-aldosterone system in patients with obesity and COVID-19, and discuss how these impairments may underlie the increased susceptibility and more detrimental outcomes of COVID-19 in people with obesity. Clearly, this has important implications for preventive measures, vaccination, and future therapeutic strategies to combat COVID-19. Furthermore, we will highlight important knowledge gaps and provide suggestions for future research and recommendations for policy actions. Since many new reports on COVID-19 rapidly appear, the present perspective should be seen as a focus for discussion to drive forward further understanding, research initiatives, and clinical management of COVID-19.