ARTÍCULO

Increased consumption of virgin olive oil, nuts, legumes, whole grains, and fish promotes HDL functions in humans

Autores: Hernaez, A. (Autor de correspondencia); Sanllorente, A. ; Castaner, O.; Martínez González, Miguel Ángel; Ros, E.; Pinto, X.; Estruch, R.; Salas-Salvado, J. ; Corella, D. ; Alonso-Gomez, A. M.; Serra-Majem, L. ; Fiol, M. ; Lapetra, J. ; Gomez-Gracia, E.; de la Torre, R.; Lamuela-Raventos, R. M.; Fito, M. (Autor de correspondencia)
Título de la revista: MOLECULAR NUTRITION AND FOOD RESEARCH
ISSN: 1613-4125
Volumen: 63
Número: 6
Páginas: 1800847
Fecha de publicación: 2019
Lugar: WOS
Resumen:
Scope To evaluate whether increases in the consumption of cardioprotective food groups (virgin olive oil, nuts, fruits/vegetables, legumes, whole grains, fish, and wine) are associated with improvements in high-density lipoprotein (HDL) functions in high cardiovascular risk subjects. Methods and Results The association between 1-year changes in food group consumption and HDL functionality traits in 296 high cardiovascular risk subjects is assessed. Increases in virgin olive oil (10 g d(-1)) and whole grain consumption (25 g d(-1)) are associated with increments in cholesterol efflux capacity (+0.7%, P = 0.026, and +0.6%, P = 0.017, respectively). Increases in nut (30 g d(-1)) and legume intake (25 g d(-1)) are linked to increments in paraoxonase-1 activity (+12.2%, P = 0.049, and +11.7%, P = 0.043, respectively). Legume intake increases are also related to decreases in cholesteryl ester transfer protein activity (-4.8%, P = 0.028). Fish consumption increments (25 g d(-1)) are associated with increases in paraoxonase-1 activity (+3.9%, P = 0.030) and declines in cholesteryl ester transfer protein activity (-1.6%, P = 0.021), HDL cholesterol concentrations (-1.1%, P = 0.039), and functions related to HDL levels (cholesterol efflux capacity, -1.1%, P = 0.010). Conclusion Increases in the consumption of virgin olive oil, nuts, legumes, whole grains, and fish (achievable through a regular diet) were associated with improvements in HDL functions in high cardiovascular risk subjects.