Association between lifestyle and hypertriglyceridemic waist phenotype in the PREDIMED-Plus study

Autores: Fernandez-Garcia, J. C. ; Munoz-Garach, A. ; Martínez González, Miguel Ángel; Salas-Salvado, J. ; Corella, D. ; Hernáez, A.; Romaguera, D. ; Vioque, J. ; Alonso-Gomez, A. M. ; Wärnberg, Julia; Martínez Hernández, Alfredo; Serra-Majem, L. ; Estruch, R. ; Lapetra, J. ; Pinto, X. ; Tur, J. A. ; Garcia-Rios, A. ; Molina, L. G. ; Gaforio, J. J. ; Matia-Martin, P. ; Daimiel, L. ; Sanchez, V. M. ; Vidal, J. ; Prieto, L. ; Ros, E. ; Goni, N. ; Babio, N. ; Ortega-Azorin, C. ; Castaner, O. ; Konieczna, J. ; Barandiaran, L. N. ; Vaquero-Luna, J. ; Benavente-Marin, J. C. ; Zulet Alzórriz, María de los Ángeles; Sánchez Villegas, María Almudena; Sacanella, E. ; Huelgas, R. G. ; Miro-Moriano, L. ; Gimenez-Gracia, M. ; Julibert, A. ; Razquin Burillo, Cristina; Basora, J. ; Portoles, O. ; Goday, A. ; Galmes-Panades, A. M. ; Lopez-Garcia, C. M. ; Moreno-Rodriguez, A. ; Toledo Atucha, Estefanía; Diaz-Lopez, A. ; Fito, M. ; Tinahones, F. J. (Autor de correspondencia); Bernal-Lopez, M. R. (Autor de correspondencia); PREDIMED-Plus Investigators
Título de la revista: OBESITY
ISSN: 1930-7381
Volumen: 28
Número: 3
Páginas: 537 - 543
Fecha de publicación: 2020
Lugar: WOS
Objective The hypertriglyceridemic waist (HTGW) phenotype is characterized by abdominal obesity and high levels of triglycerides. In a cross-sectional assessment of PREDIMED-Plus trial participants at baseline, HTGW phenotype prevalence was evaluated, associated risk factors were analyzed, and the lifestyle of individuals with metabolic syndrome and HTGW was examined. Methods A total of 6,874 individuals aged 55 to 75 with BMI >= 27 and < 40 kg/m(2) were included and classified by presence (HTGW(+)) or absence (HTGW(-)) of HTGW (waist circumference: men >= 102 cm, women >= 88 cm; fasting plasma triglycerides >= 150 mg/dL). Analytical parameters and lifestyle (energy intake and expenditure) were analyzed. Results A total of 38.2% of the sample met HTGW(+) criteria. HTGW(+) individuals tended to be younger, have a greater degree of obesity, be sedentary, and be tobacco users. They had higher peripheral glucose, total cholesterol, and low-density lipoprotein cholesterol levels; had lower high-density lipoprotein cholesterol levels; and had increased prevalence of type 2 diabetes mellitus. Mediterranean diet (MedDiet) adherence and physical activity were greater in HTGW(-) patients. Age, BMI, tobacco use, total energy expenditure, hypertension, type 2 diabetes mellitus, and MedDiet adherence were associated with HTGW(+). Conclusions HTGW is a highly prevalent phenotype in this population associated with younger age, higher BMI, tobacco use, and decreased MedDiet adherence. HTGW(-) individuals were more physically active with greater total physical activity, and fewer had hypertension.