Revistas
Revista:
ACTA OTORRINOLARINGOLOGICA ESPAÑOLA
ISSN:
0001-6519
Año:
2019
Vol.:
70
N°:
3
Págs.:
151 - 157
Objectives: To characterize laryngo-pharyngeal reflux (LPR) in patients over 60 years of age.
Methods: Retrospective review of patients over 60 years of age with symptoms suspicious of LPR, seen from 2005 to 2014 at an ENT Department of an academic hospital. Eighty-five consecutive patients (54 females, 31 males) who had completed a dual-sensor 24-hour pH-metry were included (considered "gold-standard" in LPR diagnosis). Body mass index, and reflux information and interventions were revised. pH-metries were evaluated according to DeMeester & Johnson's criteria. Symptoms were assessed according to the Reflux Symptom Index (RSI) and classified as abnormal if score was ¿13. A naso-fibro-laryngoscopy enabled findings to be documented according to the Reflux Finding Score (RFS), and they were classified as abnormal if the score was ¿7.
Results: The patients' mean age was 67 years. A positive pH-metry was present in 70 patients (82.5%). Fifty patients (59%) had abnormal body mass index, and almost 90% of them had an abnormal pH-metry. Mean RSI score was 9.8, with abnormal results in 24 patients (28%). Only 20 patients (23%) with abnormal RSI had a positive pH-metry. Posterior commissure hypertrophy was the most common finding (90% of patients). Mean RFS score was 9.07, with abnormal results in 69 patients (81%). Sixty-one patients (70%) with abnormal RFS had a positive pH-metry. Only 18 patients (20%) had coincidental abnormal pH-metry, RSI, and RFS.
Conclusions: In ageing patients, abnormal body mass index is strongly associated with abnormal pH-metry. RSI is a weak indicator of LPR, whereas RFS has a moderate value.
Revista:
ACTA OTORRINOLARINGOLOGICA ESPAÑOLA
ISSN:
0001-6519
Año:
2019
Vol.:
70
N°:
5
Págs.:
306 - 309
Autores:
Macias, A. R. (Autor de correspondencia); Zaballos, M. T. P.; de Miguel, A. R.; et al.
Revista:
OTOLOGY AND NEUROTOLOGY
ISSN:
1531-7129
Año:
2017
Vol.:
38
N°:
10
Págs.:
E429 - E437
Hypothesis: Modiolar proximity of the cochlear implant electrodes and low impedance values have a positive effect on electrical pitch discrimination. Background: The proximity of the cochlear electrode to the modiolar wall can determine changes in tissue and fluid environment. With the onset of soft-surgery techniques, the trauma caused during surgery has been reduced, minimizing fibrous growth. Methods: Computed tomography-scan measurements of electrode-inner wall distance and psychoacoustic electrode discrimination tests were done. Neural Response Telemery and impedance data were used in the study. Results: It was found that patients fitted with perimodiolar arrays have lower impedance values and smaller electrodeinner wall distances than those fitted with straight arrays. These variables were significantly correlated to electrode discrimination. It was found that a closer distance to the modiolus also results in better electrode discrimination. Conclusion: Perimodiolar electrodes could be a better solution in terms of pitch discrimination both because they are closer to the modiolus and because their impedance is lower.
Revista:
CLINICAL OTOLARYNGOLOGY
ISSN:
1749-4478
Año:
2016
Vol.:
41
N°:
5
Págs.:
606-611
Revista:
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
ISSN:
0937-4477
Año:
2013
Vol.:
270
N°:
1
Págs.:
45 - 52
The purpose of this study is to determine if surgical approach to the inner ear is feasible without generating a hearing loss in an animal model. Five Macaca fascicularis were used as experimental animals and followed up for 27 months. Mastoidectomy, posterior tympanotomy and promontorial cochleostomy were performed on four specimens and one specimen was kept as control animal. Before and after drilling and exposing the endosteal layer and the membranous labyrinth, otoacustic emissions (dPOAE) and auditory brainstem responses (ABR) were used to test hearing. In vivo experimental studies prove it is reliable to expose the membranous labyrinth without causing hearing loss. dPOAE were present after 3, 6, 12, 24 and 26 months of follow-up. Regarding the ABR results from the four M. fascicularis in which a cochleostomy has been carried out, auditory thresholds are within the 20-30 dB interval at 27 months of follow-up. Experimental studies support clinical experiences indicating it is feasible to surgically approach the membranous labyrinth of the cochlea without damaging its hearing function.
Revista:
FIAPAS
ISSN:
1135-3511
Año:
2012
Vol.:
141
Págs.:
1 - 7
Revista:
REVUE DE LARYNGOLOGIE - OTOLOGIE - RHINOLOGIE
ISSN:
0035-1334
Año:
2011
Vol.:
132
N°:
3
Págs.:
153-155.
The treatment of patients with idiopathic sudden sensorineural hearing loss must be performed as an emergency measure in order to prevent long term hearing deficit. Steroids in monotherapy provide the best outcome. There is some controversy regarding the most efficient route but in order to prevent side effects, intratympanic treatment is the preferred choice, especially in diabetic patients. We here present the case of a patient that developed hyperglycemia after systemic and intratympanic dexamethasone treatment for sudden hearing loss. We conclude that after intratympanic treatment great caution must be taken.
Revista:
AUDIOL NEURO-OTOL
ISSN:
1420-3030
Año:
2010
Vol.:
15
N°:
6
Págs.:
399 - 406
Revista:
REVISTA DE NEUROLOGIA
ISSN:
0210-0010
Año:
2010
Vol.:
50
N°:
2
Págs.:
65 - 71
The findings of our study both agree and disagree with some earlier works from the literature, which suggests that patients with AD may have their own auditory pattern.
Revista:
REVISTA DE NEUROLOGIA
ISSN:
0210-0010
Año:
2010
Vol.:
50
N°:
2
Págs.:
65 - 71
Introduction: Despite the different epidemiological, neurophysiological and morphological studies published in the literature, it is still not known for sure whether there is a relation between Alzheimer's disease (AD) and peripheral hearing loss. In this work we conduct an auditory study in patients with AD and in volunteer controls in order to investigate this possible relationship.
Subjects and methods: The sample studied consisted of 14 patients with a clinical diagnosis of probable AD (age: 79 Y 6 years) and 14 volunteers (age: 76 Y 5 years) who visited the Clinica Universidad de Navarra. After applying a set of thorough criteria to preclude any previous hearing problems, all the participants underwent a subjective hearing assessment by means of pure-tone threshold audiometry and vocal audiometry and an objective auditory assessment using a tympanometry study, stapedial reflex, otoacoustic emissions and brainstem auditory evoked potentials. For the analysis, patients with AD and controls were paired homogenously by sex and age.
Results: The main obstacle hindering the study was to recruit the participants, due to the fact that they did not see any direct benefit from the study and it demanded an excessive amount of their time. Pure-tone threshold audiometry showed that patients with AD had a pattern of greater hearing loss for acute frequencies, with statistically significant differences. No significant differences were found in the analysis of the rest of the subjective and objective hearing tests.
Conclusions: The findings of our study both agree and disagree with some earlier works from the literature, which suggests that patients with AD may have their own auditory pattern.
Nacionales y Regionales
Título:
Descifrando la disociación de resultados en pruebas vestibulares de pacientes con enfermedad de Méniere unilateral
Código de expediente:
PI19/00414
Financiador:
INSTITUTO DE SALUD CARLOS III
Convocatoria:
2019 AES Proyectos de investigación
Fecha de inicio:
01/01/2020
Fecha fin:
31/12/2023
Importe concedido:
68.970,00€
Otros fondos:
Fondos FEDER