Revistas
Revista:
MEDICINE (ELSEVIER)
ISSN 0304-5412
Vol. 12
N° 86
Año 2019
Págs.5023 - 5036
Psychotic disorders are an heterogeneous group of diseases characterized by a symptomatology related to break with reality. Because its severity, schizophrenia is the most relevant disorder, involving the both subject and his family. Classified as neurodevelopmental disease, whose symptoms appear during pregnancy, which evolves to chronicity, and in which relapses along the life are frequent. In the latest version of the classification of the American Psychiatric Association (DSM-5) all psychotic disorders are classified in the same chapter.
Revista:
MEDICINE (ELSEVIER)
ISSN 0304-5412
Vol. 12
N° 86
Año 2019
Págs.5075 - 5080
Although antipsychotic drugs are effective against positive psychosis symptoms, their effectiveness is limited against negative ones. Treatment has to be supplemented with non-pharmacological measures (psychoeducation, cognitive rehabilitation, social skills training). One of the greatest challenges is therapeutic adherence, being crucial to achieve a good evolution. The best therapeutic option for treatment-resistant schizophrenia is clozapine.