Nuestros investigadores

Francisco Javier García Martinez

Publicaciones científicas más recientes (desde 2010)

Autores: Pascual, J. C.; Alvarez-Chinchilla, P. ; et al.
Revista: EXPERIMENTAL DERMATOLOGY
ISSN 0906-6705  Vol. 28  2019  págs. 13 - 13
Autores:  Lopez-Martin, I.;
Revista: ACTAS DERMO-SIFILIOGRAFICAS
ISSN 0001-7310  Vol. 109  Nº 6  2018  págs. 547 - 548
Autores: Poveda, I. , (Autor de correspondencia); Vilarrasa, E.; Martorell, A.; et al.
Revista: AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
ISSN 1175-0561  Vol. 19  Nº 5  2018  págs. 771 - 777
BackgroundSerum zinc levels in patients with hidradenitis suppurativa (HS) have not been previously studied.ObjectiveThe aim was to investigate the association between HS and serum zinc levels.MethodsA multicenter, prospective clinical and analytical case-control study was designed to assess the possible association between HS and serum zinc levels. Consecutive patients with moderate or severe HS (Hurley II or III exclusively) were enrolled. A control population was recruited from primary care clinics. Fasting blood samples were extracted from each patient and serum zinc levels determined. Candidate predictors for low serum zinc levels were determined using logistic regression models.ResultsIn total, 122 patients with HS and 122 control subjects were studied. Of the 122 HS patients, 79 (64.8%) were Hurley II and 43 (35.2%) were Hurley III. Low serum zinc levels (83.3 mu g/dL) were more prevalent in HS (adjusted odds ratio [ORa] 6.7, P<0.001). After logistic regression analysis, low serum zinc levels were associated with Hurley III (ORa 4.4, P<0.001), Dermatology Life Quality Index9 (ORa 3.1, P=0.005), number of affected sites3 (ORa 2.4, P=0.042), genital location (ORa 2.9, P=0.009), and perineal location (ORa 2.5, P=0.025).ConclusionLow serum zinc levels are more prevalent in HS than in a healthy population, an indicator that may also be associated with disease severity.
Autores: Martorell, A.; Wortsman, X. ; Alfageme, F. ; et al.
Revista: DERMATOLOGIC SURGERY
ISSN 1076-0512  Vol. 43  Nº 8  2017  págs. 1065 - 1073
BACKGROUND Staging and monitoring of patients with hidradenitis suppurativa (HS) have been traditionally based on clinical findings. However, the physical examination may show important limitations because of its poor sensitivity for differentiating between different lesion subtypes, and its low sensitivity to define the disease's activity. OBJECTIVE To develop a consensus ultrasound (US) report that could summarize the relevant anatomical characteristics and staging of patients considering the experience of radiologists and dermatologists working on imaging of HS. METHODS A questionnaire on different aspects related to US examination in HS was performed. A working group, called DERMUS, composed of doctors from 9 countries who have been working in dermatologic US applied in patients with HS on a regular basis were included to evaluate the different items provided. RESULTS A consensus US report to evaluate HS patients was established. CONCLUSION The authors present the first attempt to define a HS standardized sonographic report. This model would be the first effort to include this imaging technique as the first elective medical test for staging and monitoring patients, which can support therapeutic decisions by providing earlier, objective, deeper, anatomical, and comparative evaluations in this difficult to treat disease.