Nuestros investigadores

Pedro Antonio de la Rosa Fernández Pacheco

Publicaciones científicas más recientes (desde 2010)

Autores: Fresán, Ujué, (Autor de correspondencia); Bes-Rastrollo, Maira; Segovia-Siapco, G.; et al.
Revista: EUROPEAN JOURNAL OF NUTRITION
ISSN 1436-6207  Vol. 58  Nº 3  2019  págs. 1271 - 1282
PURPOSE: To prospectively evaluate the association of the Mediterranean-DASH diet intervention for neurodegenerative delay (MIND) diet and the Mediterranean diet (and their components), and depression risk. METHODS: We followed-up (median 10.4 years) 15,980 adults initially free of depression at baseline or in the first 2 years of follow-up. Food consumption was measured at baseline through a validated food-frequency questionnaire, and was used to compute adherence to the MIND and the Mediterranean diets. Relationships between these two diets and incident depression were assessed through Cox regression models. RESULTS: We identified 666 cases of incident depression. Comparing the highest versus the lowest quartiles of adherence, we found no association of the MIND diet and incident depression. This relation was statistically significant for the Mediterranean diet {hazard ratio (HR) 0.75, [95% confidence interval (95% CI) 0.61, 0.94]; p¿<¿0.01}, although with departure from linearity. A reduced depression risk was associated with higher consumption of both fruits and nuts [HR 0.82 (95% CI 0.69, 0.96); p¿=¿0.02], moderate nuts consumption [HR 0.77 (95% CI 0.64, 0.93); p¿=¿0.01], and avoidance of fast/fried food [HR 0.63 (95% CI 0.41, 0.96); p¿=¿0.03]. CONCLUSIONS: The Mediterranean diet was associated with reduced depression risk, but we found no evidence of such an association for the MIND diet.
Autores: Benjamín Prieto-Damm; de la Rosa, Pedro Antonio; Lopez-del Burgo, C; et al.
Revista: DRUG AND ALCOHOL DEPENDENCE
ISSN 0376-8716  Vol. 199  2019  págs. 27-34
Introduction: Structured and unstructured leisure are known protective and risk factors, respectively, for alcohol consumption during adolescence. However, little is known about the interaction between the two leisure types and alcohol consumption. Method: A cross-sectional study was performed among high-school students in El Salvador and Peru. Schooled adolescents, aged 13¿18 (N=5,640), completed a self-administered questionnaire about risk behaviors, including their leisure activities and whether they had consumed alcoholic beverages. They were classified into tertiles of the amount of time of both structured and unstructured activities. A non-conditional multivariate logistic regression was conducted to evaluate the association of both types of leisure with alcohol consumption. We also used a likelihood ratio test to assess the potential interaction of structured and unstructured leisure time in alcohol consumption. Results: Alcohol consumption was much more frequent among adolescents in the highest tertile of unstructured leisure time compared to the lowest one, and less frequent among those from the highest tertile of structured leisure time compared to the lowest one. We did not find an interaction effect between structured and unstructured leisure time with regard to initiation of alcohol consumption. Discussion: The study suggests that structured leisure is not enough to compensate for the possible harmful effect of unstructured leisure. Parents, educators and policy