Detalle Publicación

ARTÍCULO

Level of IgG4 anti-desmoglein 3 antibodies correlates with disease activity in patients with pemphigus vulgaris

Título de la revista: AUTOIMMUNE AND INFECTIOUS DISEASE
ISSN: 2470-1025
Volumen: 1
Número: 1
Fecha de publicación: 2015
Resumen:
Results: The anti-desmoglein 3 specific immunoglobulin G1 and immunoglobulin G4 subclass study revealed that sera from patients with clinically inactive disease have lower anti-desmoglein 3 immunoglobulin G4 subclass antibody levels than sera from those with active disease by enzyme-linked immunosorbent assay (p=0.03). However, there was no statistically significant difference for immunoglobulin G1 between the two groups. Similarly, the presence of immunoglobulin G subclasses of anti-skin antibodies by indirect immunofluorescence between the two groups was not statistically significantly different. Conclusion: Levels of anti-desmoglein 3 immunoglobulin G4 subclass autoantibodies look very adequate to compare patients in remission with clinically active patients with pemphigus vulgaris (p=0.03
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