Detalle Publicación

Successful Colon Cancer Eradication after Chemoimmunotherapy Is Associated with Profound Phenotypic Change of Intratumoral Myeloid Cells

Autores: Medina Echeverz, José; Fioravanti, Jessica; Zabala, Maider; Ardaiz Iriarte, Nuria María; Prieto Valtueña, Jesús María; Berraondo López, Pedro
Título de la revista: JOURNAL OF IMMUNOLOGY
ISSN: 0022-1767
Volumen: 186
Número: 2
Páginas: 807 - 815
Fecha de publicación: 2011
Resumen:
IL-12 is a potent immunostimulatory cytokine, but its impact as an antitumor drug in clinical practice is limited. Upsurge of regulatory T cells (Treg) in the tumor milieu has been proposed to limit the efficacy of the treatment.
DOI: https://doi.org/http://dx.doi.org/10.4049/jimmunol.1001483
Impacto:
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