Detalle Publicación

'Obesities': position statement on a complex disease entity with multifaceted drivers

Autores: Yárnoz-Esquiroz, P.; Olazarán, L.; Aguas-Ayesa, M.; Perdomo Zelaya, Carolina María; García Goñi, Marta; Silva Frojan, Camilo; Fernández-Formoso, J. A.; Escalada San Martín, Francisco Javier; Montecucco, F. ; Portincasa, P.; Fruhbeck Martínez, Gema (Autor de correspondencia)
Título de la revista: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
ISSN: 0014-2972
Volumen: 52
Número: 7
Páginas: e13811
Fecha de publicación: 2022
Resumen:
Academic medicine fosters research that moves from discovery to translation, at the same time as promoting education of the next generation of professionals. In the field of obesity, the supposed integration of knowledge, discovery and translation research to clinical care is being particularly hampered. The classification of obesity based on the body mass index does not account for several subtypes of obesity. The lack of a universally shared definition of "obesities" makes it impossible to establish the real burden of the different obesity phenotypes. The individual's genotype, adipotype, enterotype and microbiota interplays with macronutrient intake, appetite, metabolism and thermogenesis. Further investigations based on the concept of differently diagnosed "obesities" are required.
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