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Milk and dairy products intake is related to cognitive impairment at baseline in Predimed plus trial

Autores: Muñoz-Garach, A.; Cornejo-Pareja, I.; Martínez González, Miguel Ángel; Bullo, M.; Corella, D.; Castañer, O.; Romaguera, D.; Vioque, J.; Alonso-Gómez, A. M.; Warnberg, J.; Martínez Hernández, Alfredo; Serra-Majem, L.; Estruch, R.; Bernal-López, M. R.; Lapetra, J.; Pinto, X.; Tur, J. A.; López-Miranda, J.; Bueno-Cavanillas, A.; Delgado-Rodríguez, M.; Matía-Martín, P.; Daimiel, L.; Sánchez, V. M.; Vidal, J.; Prieto, L.; Ros, E.; Fernández-Aranda, F.; Camacho-Barcia, L.; Ortega-Azorín, C.; Soria, M.; Fiol, M.; Compan-Gabucio, L.; Goicolea-Guemez, L.; Pérez-López, J.; Goñi, N.; Pérez-Cabrera, J.; Sacanella, E.; Fernández-García, J. C.; Miro-Moriano, L.; Giménez-Gracia, M.; Razquin Burillo, Cristina; Paz-Graniel, I.; Guillem, P.; Zomeno, M. D.; Moñino, M.; Oncina-Canovas, A.; Salaverria-Lete, I.; Toledo Atucha, Estefanía; Salas-Salvadó, J.; Schroder, H.
Título de la revista: MOLECULAR NUTRITION AND FOOD RESEARCH
ISSN: 1613-4125
Volumen: 65
Número: 7
Páginas: e2000728
Fecha de publicación: 2021
Resumen:
Scope To examine the association between milk and dairy products intake and the prevalence of cognitive decline among Spanish individuals at high cardiovascular risk. Methods and results Cross-sectional analyses are performed on baseline data from 6744 adults (aged 55-75 years old). Intake of milk and dairy products is estimated using a food frequency questionnaire grouped into quartiles. The risk of developing cognitive impairment is based on the Mini-Mental State Examination (MMSE). A higher prevalence of cognitive decline was found in subjects who consumed more grams. Patients with worse MMSE score (10-24) consumed a mean of 395.14 +/- 12.21 g, while patients with better MMSE score (27-30) consumed a mean of 341.23 +/- 2.73 g (p < 0.05). Those subjects with the lower milk consumption (<220 g/day) had a higher MMSE score (28.35 +/- 0.045). Higher intake of fermented dairy products was observed in participants with a lower MMSE score (OR 1.340, p = 0.003). A positive correlation was found between the consumption of whole milk and the MMSE score (r = 0.066, p < 0.001). Conclusions These findings suggest that greater consumption of milk and dairy products could be associated with greater cognitive decline according to MMSE. Conversely, consumption of whole-fat milk could be linked with less cognitive impairment in the cross-sectional study.
DOI: https://doi.org/10.1002/mnfr.202000728
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