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ARTÍCULO

Screening of Fabry disease in patients with chest pain without obstructive coronary artery disease

Autores: Hernández Hernández, Aitor; Diez-López, C.; Azevedo, O.; Palomino-Doza, J.; Alfonso, F.; Fuentes-Cañamero, M.F.; Mogollón Jiménez, M.V.; Casanova Rodríguez, C.; Ruz, A.; Tirón, C.; Climent, V.; Garcia-Pavia, P. (Autor de correspondencia)
Título de la revista: JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
ISSN: 1937-5395
Volumen: 14
Número: 5
Páginas: 948 - 950
Fecha de publicación: 2021
Resumen:
Identification of Anderson-Fabry disease (AFD) in cardiac patients has been restricted so far to patients with left ventricular hypertrophy. Coronary microvascular dysfunction has been described in AFD with and without cardiac hypertrophy and may represent the only manifestation in AFD patients, offering a possible earlier diagnosis. We studied the prevalence of AFD in 663 patients with chest pain with normal or non-obstructive coronary arteries. The overall prevalence of AFD in this cohort was only 0.15% (1/663). AFD is not a frequent cause of chest pain without obstructive coronary artery disease and screening efforts should not be conducted in this patient population.
DOI: https://doi.org/10.1007/s12265-020-10097-2
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