Objective To analyse the cosmetic features of 12 gels used in clinical practice for acne treatment. Material and methods Observational and descriptive study in 50 patients evaluated in the Hospital del Sureste between February and April of 2015. The different gels were provided in a transparent container and the patients evaluated odour, colour, easy to extend, and whether the gel remained over the skin after its application, and the sticky sensation. The patients also gave an overall score to each gel. Results Statistically significant differences in the evaluation of the different gels. The odour and the sticky sensation over the skin are the two variables most taken into account when the cosmetic features are evaluated by the patients. Conclusion The general perception of the cosmetics features of different gels currently used for the treatment of acne varies significantly depending on the gel used.