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A methodology for numerically analysing the hepatic artery haemodynamics during B-TACE: a proof of concept

Autores: Aramburu Montenegro, Jorge (Autor de correspondencia); Antón Remírez, Raúl; Rivas Nieto, Alejandro; Ramos González, Juan Carlos; Sánchez Larraona, Gorka; Sangro Gómez-Acebo, Bruno Carlos; Bilbao Jaureguizar, José Ignacio
Título de la revista: COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
ISSN: 1025-5842
Volumen: 22
Número: 5
Páginas: 518 - 532
Fecha de publicación: 2019
Resumen:
Balloon-occluded transarterial chemoembolisation (B-TACE) is an intraarterial transcatheter treatment for liver cancer. In B-TACE, an artery-occluding microballoon catheter occludes an artery and promotes collateral circulation for drug delivery to tumours. This paper presents a methodology for analysing the haemodynamics during B-TACE, by combining zero-dimensional and three-dimensional modelling tools. As a proof of concept, we apply the methodology to a patient-specific hepatic artery geometry and analyse two catheter locations. Results show that the blood flow redistribution can be predicted in this proof-of-concept study, suggesting that this approach could potentially be used to optimise catheter location.
DOI: https://doi.org/10.1080/10255842.2019.1567720
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