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EDITORIAL

LKB1: Controlling quiescence and genomic integrity at home

Autores: Berasain Lasarte, María del Carmen (Autor de correspondencia); Ávila Zaragoza, Matías Antonio
Título de la revista: TRENDS IN ENDOCRINOLOGY AND METABOLISM
ISSN: 1043-2760
Volumen: 29
Número: 10
Páginas: 668 - 670
Fecha de publicación: 2018
Resumen:
The pleiotropic liver kinase B1 (LKB1) controls metabolism, cell polarity, and proliferation in an apparently cell-and context-specific manner. A recent study in Cell Reports has demonstrated that LKB1 is essential to maintain the characteristic quiescence of the liver and to secure genomic integrity during liver regeneration independently of AMPK.
DOI: https://doi.org/10.1016/j.tem.2018.03.017
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