Detalle Publicación

Microbiological diagnosis of biofilm-related infections

Autores: Macia, M. D. (Autor de correspondencia); del Pozo León, José Luis; Diez-Aguilar, M.; Guinea, J.
Título de la revista: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
ISSN: 0213-005X
Volumen: 36
Número: 6
Páginas: 375 - 381
Fecha de publicación: 2018
Resumen:
Biofilm-related infections represent a serious health problem, accounting for 65-80% of all infections. The infections are generally chronic and characterized by the persistence of the microorganism, due to the increased resistance of biofilms to both the immune system and antimicrobials. Biofilms can be located to almost every human body tissue and on exogenous devices such as catheters, pacemakers, prosthetic material, implants, urinary catheters, etc. Traditional antimicrobial susceptibility studies in clinical microbiology laboratories have lied on the study of planktonic form of microorganisms. However, this approach might lead to miss the biofilm characteristics and to a treatment failure. Microbiological diagnosis and antimicrobial susceptibility studies of biofilm-related infections are complex and, nowadays, represent a challenge that clinicians and microbiologists have to address as a team in the absence of consensus or standardized protocols. (C) 2017 Elsevier Espana, S.L.U. and Sociedad Espanola de Enfermedades lnfecciosas y Microbiologia Clinica. All rights reserved.