Detalle Publicación

ARTÍCULO

Generation of iPSC from cardiac and tail-tip fibroblasts derived from a second heart field reporter mouse

Autores: Linares Acosta, Javier; Arellano-Viera, E.; Iglesias García, Olalla; Ferreira Espinar, María del Carmen; Iglesias López, Elena; Abizanda Sarasa, Gloria María; Prosper Cardoso, Felipe; Carvajal Vergara, Xonia
Título de la revista: STEM CELL RESEARCH
ISSN: 1873-5061
Volumen: 16
Número: 3
Páginas: 617 - 621
Fecha de publicación: 2016
Resumen:
Mef2c Anterior Heart Field (AHF) enhancer is activated during embryonic heart development and it is expressed in multipotent cardiovascular progenitors (CVP) giving rise to endothelial and myocardial components of the outflow tract, right ventricle and ventricular septum. Here we have generated iPSC from transgenic Mef2c-AHF-Cre x Ai6(RCLZsGreen) mice. These iPSC will provide a novel tool to investigate the AHF-CVP and their cell progeny. (C) 2016 The Authors. Published by Elsevier B.V.
DOI: https://doi.org/10.1016/j.scr.2016.03.006
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