Detalle Publicación

ARTÍCULO

Non-invasive in vivo imaging of cardiac stem/progenitor cell biodistribution and retention after intracoronary and intramyocardial delivery in a swine model of chronic ischemia reperfusion injury

Autores: Collantes Martínez, María; Pelacho Samper, Beatriz; García Velloso, María José; Gavira Gómez, Juan José; Abizanda Sarasa, Gloria María; Palacios I; Rodriguez-Borlado L; Álvarez V; Prieto Azcárate, Elena; Ecay Ilzarbe, Marga; Larequi Ardanáz, Eduardo; Peñuelas Sánchez, Iván; Prosper Cardoso, Felipe
Título de la revista: JOURNAL OF TRANSLATIONAL MEDICINE
ISSN: 1479-5876
Volumen: 15
Número: 1
Páginas: 56
Fecha de publicación: 2017
Resumen:
PET/CT imaging of 18F-FDG-labeled CSC allows quantifying biodistribution and acute retention of implanted cells in a clinically relevant pig model of chronic myocardial infarction. Similar levels of acute retention are achieved when cells are IM or IC administered. However, acute cell retention does not correlate with cell engraftment, which is improved by IM injection.
DOI: https://doi.org/10.1186/s12967-017-1157-0.
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