Detalle Publicación

ARTÍCULO

Development of a liver-specific Tet-on inducible system for AAV vectors and its application in the treatment of liver cancer

Autores: Vanrell, Lucía; Di Scala, Marianna; Blanco, Laura; Otano Andrés, Itziar; Gil Fariña, Irene; Baldim, Victor; Pañeda Rodríguez, María Astrid; Berraondo López, Pedro; Beattie, Stuart G.; Chtarto, Abdelwahed; Tenenbaum, Lilianne; Prieto Valtueña, Jesús María; González Aseguinolaza, Gloria
Título de la revista: Molecular Therapy
ISSN: 1525-0016
Volumen: 19
Número: 7
Páginas: 1245 - 1253
Fecha de publicación: 2011
Resumen:
Recombinant adeno-associated virus (rAAV) are effective gene delivery vehicles that can mediate long-lasting transgene expression. However, tight regulation and tissue-specific transgene expression is required for certain therapeutic applications.
DOI: https://doi.org/http://dx.doi.org/10.1038/mt.2011.37
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