Detalle Publicación

ARTÍCULO

Identification of genetic variants in pharmacokinetic genes associated with Ewing Sarcoma treatment outcome

Autores: Ruiz-Pinto, S.; Pita, G.; Patiño García, Ana; García-Miguel, P. (Corrector); Alonso, J.; Pérez-Martínez, A.; Sastre, A.; Gómez-Mariano, G.; Lissat, A.; Scotlandi, K.; Serra, M.; Ladenstein, R.; Lapouble, E.; Pierron, G.; Kontny, U.; Picci, P.; Kovar, H.; Delattre, O.; González-Neira, A.
Título de la revista: ANNALS OF ONCOLOGY
ISSN: 0923-7534
Volumen: 27
Número: 9
Páginas: 1788-93
Fecha de publicación: 2016
Resumen:
Using an integrated pathway-based approach, we identified polymorphisms in ABCC6, ABCB1 and CYP2C8 associated with OS. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in ES.
DOI: https://doi.org/10.1093/annonc/mdw234
Impacto:
Google Scholar