Detalle Publicación

ART%EF%BF%BD%EF%BF%BDCULO

Abdominal aortic aneurysm: from clinical imaging to realistic replicas

Título de la revista: JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
ISSN: 0148-0731
Volumen: 136
Número: 1
Páginas: 014502 - 014502-5
Fecha de publicación: 2013
Resumen:
The goal of this work is to develop a framework for manufacturing nonuniform wall thickness replicas of abdominal aortic aneurysms (AAAs). The methodology was based on the use of computed tomography (CT) images for virtual modeling, additive manufacturing for the initial physical replica, and a vacuum casting process and range of polyurethane resins for the final rubberlike phantom. The average wall thickness of the resulting AAA phantom was compared with the average thickness of the corresponding patient-specific virtual model, obtaining an average dimensional mismatch of 180 lm (11.14%). The material characterization of the artery was determined from uniaxial tensile tests as various combinations of polyurethane resins were chosen due to their similarity with ex vivo AAA mechanical behavior in the physiological stress configuration. The proposed methodology yields AAA phantoms with nonuniform wall thickness using a fast and low-cost process. These replicas may be used in benchtop experiments to validate deformations obtained with numerical simulations using finite element analysis, or to validate optical methods developed to image ex vivo arterial deformations during pressure-inflation testing.
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