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Six-transmembrane epithelial antigen of prostate 4 and neutrophil gelatinase-associated lipocalin expression in visceral adipose tissue is related to iron status and inflammation in human obesity

Autores: Catalán Goñi, Victoria; Gómez Ambrosi, Javier; Rodríguez Murueta-Goyena, Amaia; Ramírez, Beatriz; Rotellar Sastre, Fernando; Valentí Azcarate, Víctor; Silva Frojan, Camilo; Gil Calvo, María Jesús; Salvador Rodríguez, Javier; Fruhbeck Martínez, Gema
Título de la revista: EUROPEAN JOURNAL OF NUTRITION
ISSN: 1436-6207
Volumen: 52
Número: 6
Páginas: 1587-1595
Fecha de publicación: 2013
Resumen:
These findings represent the first observation that STEAP4 and NGAL mRNA and protein levels in human VAT are related to iron status. Moreover, STEAP4 and NGAL are associated with pro-inflammatory markers suggesting their potential involvement in the low-grade chronic inflammation accompanying obesity.
DOI: https://doi.org/10.1007/S00394-012-0464-8
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