Nuestros investigadores

Leire Aguado Gil

Departamento
Dermatología
Clínica Universidad de Navarra. Clínica Universidad de Navarra
Facultad de Ciencias. Universidad de Navarra
Líneas de investigación
Malformaciones vasculares, Genodermatosis, Queratomas actínicos
Índice H
9, (WoS, 16/05/2017)

Publicaciones científicas más recientes (desde 2010)

Autores: Aguado-Gil, L; Alberdi Soto, M; et al.
Revista: JOURNAL OF COSMETIC AND LASER THERAPY
ISSN 1476-4172  Vol. 17  Nº 6  2015  págs. 304-06
Epidermal nevi are benign proliferations of the epidermis for which different treatments have been used with disappointing results due to their recurrences and anesthetic scars. Topical therapies have generally been ineffective and surgical treatment provides more definitive results, but with high risk of scarring. In recent years, multiple laser modalities have been described for the treatment of these lesions. In the literature, there are no reported cases of treatment of these lesions with Neodymium-doped Yttrium aluminum garnet (Nd:YAG) laser. We present the case of a 3-year-old patient with a hemicorporal epidermal nevus treated with Nd:YAG laser at an early stage with good results.
Autores:  et al.
Revista: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
ISSN 0190-9622  Vol. 72  Nº Supl. 1  2015  págs. S73-5
Autores: Núñez, Jorge María; Aguado-Gil, L; et al.
Revista: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
ISSN 0190-9622  Vol. 72  2015  págs. 151-8
Topical rapamycin associated with PDL seems to be an effective treatment for PWS in patients with SWS.
Autores: Núñez, Jorge María; Aguado-Gil, L; et al.
Revista: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
ISSN 0190-9622  Vol. 73  Nº 2  2015  págs. e73-e74
Autores: Redondo, P. ; Núñez, Jorge María; et al.
Revista: JAMA DERMATOLOGY
ISSN 2168-6068  Vol. 151  Nº 8  2015  págs. 897 - 899
Autores: Aguado-Gil, L; et al.
Revista: MEDICINE (ELSEVIER)
ISSN 0304-5412  Vol. 11  Nº 48  2014  págs. 2868-2863
Autores: Alberdi Soto, M; Aguado-Gil, L; et al.
Revista: JOURNAL OF COSMETIC AND LASER THERAPY
ISSN 1476-4172  Vol. 16  Nº 6  2014  págs. 314-6
Voriconazole is an antifungal agent mainly used against aspergillosis. Given its wide spectrum of action and limited adverse effects, it has replaced amphotericin B as the drug of choice in the prophylactic treatment of immunocompromised patients. Several adverse effects are caused by this drug with dermatological reactions accounting for 6% of the total. Such reactions include cheilitis, erythema, erosions, discoid lupus erythematosus, erythema multiforme, photosensitivity reactions, pseudoporphyria, accelerated photoaging and skin cancer. There are few reports on the accelerated photoaging caused by voriconazole and its effective treatment. Here we present the case of a 6-year-old child with a history of chronic granulomatous disease under prolonged treatment with voriconazole, who developed accelerated photoaging lesions secondary to the chronic use of this antifungal agent. Treatment was initiated using Q-switched Nd:YAG laser with good results.
Autores: Iñarrairaegui, Mercedes; et al.
Revista: JAMA DERMATOLOGY
ISSN 2168-6068  Vol. 150   Nº 6  2014  págs. 664-66
Autores: Aguado-Gil, L;
Revista: ACTAS DERMO-SIFILIOGRAFICAS
ISSN 0001-7310  Vol. 104  Nº 7  2013  págs. 617-622
Autores: Aguado-Gil, L; et al.
Revista: ANNALS OF PHARMACOTHERAPY
ISSN 1060-0280  Vol. 47  Nº 3  2013  págs. e16
This appears to be the first report of a case of TEN that occurred in a patient being treated with oral tranexamic acid. Clinicians should be made aware of this potential severe cutaneous adverse reaction that may be caused by tranexamic acid administration.
Autores: Aguado-Gil, L; et al.
Revista: JOURNAL OF COSMETIC AND LASER THERAPY
ISSN 1476-4172  Vol. 15  Nº 4  2013  págs. 207-9
Partial unilateral lentiginosis (PUL) is a rare pigmentary disorder characterized by multiple lentigines grouped within an area of normal skin, often in a segmental pattern and appearing at birth or in childhood. There is no established standard treatment for this condition. We present two cases of PUL succesfully treated with alexandrite Q-switched laser. In our cases, this laser proved to be a safe and effective treatment for cosmetically disfiguring lentigines. Special precautions are needed when treating dark-skinned patients because side effects are more likely. We propose that this modality be considered in the treatment of this rare disorder.
Autores: Basset-Seguin, N; Baumann Conzett, K; Gerritsen, MJ; et al.
Revista: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
ISSN 0926-9959  Vol. 27   Nº 1  2013  págs. 57-66
This position article summarizes those discussions and makes recommendations concerning a standardized protocol for treating OTRs, for a large randomized controlled trial to provide robust data on safety, efficacy and optimal pain control, and to provide pharmaco-economics data that can be used to support extended reimbursement in this patient group. The authors also recommend a second clinical trial to further investigate induced immunosuppression with PDT in healthy volunteers.
Autores:  et al.
Revista: ACTAS DERMO-SIFILIOGRAFICAS
ISSN 0001-7310  Vol. 104  Nº 8  2013  págs. 724-5
Autores: Paris, F; Azón, A; et al.
Revista: EXPERIMENTAL DERMATOLOGY
ISSN 0906-6705  Vol. 22  Nº 12  2013  págs. 838 - 839
Pachyonychia congenita is a rare, autosomal dominant genetic disease characterized by painful palmoplantar keratoderma and hypertrophic nail dystrophy. This disorder is caused by mutations in any one of five cytoskeletal keratin proteins, K6a, K6b, K6c, K16 and K17. Here, we describe a new p.Leu421Pro (c.1262T>C) mutation in the highly conserved helix termination motif of K16 in a large Spanish family. Bioinformatic analyses as well as previous descriptions in the literature of homologous mutations in other keratin-coding genes show that this mutation is probably causative of the disease.
Autores: Redondo, P. ; Aguado-Gil, L;
Revista: Journal of the American Academy of Dermatology
ISSN 0190-9622  Vol. 65  Nº 5  2011  págs. 893 - 906
There is significant confusion in the literature when describing vascular anomalies, and vascular malformations are often misnamed or incorrectly classified. Part I of this two-part series on the diagnosis and management of extensive vascular malformation
Autores: Aguado-Gil, L; Redondo, P. ;
Revista: PIEL
ISSN 0213-9251  Vol. 26  Nº 6  2011  págs. 285-90
Autores: Redondo, P. ; Aguado-Gil, L;
Revista: Journal of the American Academy of Dermatology
ISSN 0190-9622  Vol. 65  Nº 5  2011  págs. 909 - 923
At least nine types of vascular malformations with specific clinical and radiologic characteristics must be distinguished in the lower limbs: Klippel¿Trénaunay syndrome, port-wine stain with or without hypertrophy, cutis marmorata telangiectatica congenit
Autores: Redondo, P. ; Aguado-Gil, L;
Revista: ANALES DEL SISTEMA SANITARIO DE NAVARRA
ISSN 1137-6627  Vol. 33  Nº 3  2010  págs. 297 - 308
Las malformaciones venosas representan 2/3 de todas las malformaciones vasculares y con frecuencia son mucho más complejas de lo que realmente parecen. Los pacientes con grandes malformaciones venosas requieren un estudio analítico y radiológico profundo, así como tratamiento específico para controlar una posible coagulación intravascular localizada. Si las lesiones son extensas, especialmente en el miembro inferior, se debe estudiar la presencia de una osteoporosis subyacente con la idea de prevenir fracturas patológicas. Igualmente debe controlarse la artropatía, y valorar la realización de una sinovectomía profiláctica precoz cuando la extensión radiológica lo aconseje, con la idea de evitar daños articulares irreversibles con el paso de los años. Actualmente la escleroterapia con microespuma se preconiza como el tratamiento de elección para las malformaciones vasculares de bajo flujo. En un futuro no muy lejano la utilización de fármacos antiangiogénicos selectivos, además de las heparinas de bajo peso molecular, servirán para controlar y tratar las malformaciones venosas.
Autores: Redondo, P. ; Aguado-Gil, L; et al.
Revista: British Journal of Dermatology (Print)
ISSN 0007-0963  Vol. 162  Nº 2  2010  págs. 350 - 356
Autores: Aguado-Gil, L; Redondo, P. ;
Revista: ARCHIVES OF DERMATOLOGY
ISSN 0003-987X  Vol. 146  Nº 12  2010  págs. 1347 - 1352
: The presence of pulmonary arterial hypertension in patients with extensive slow-flow vascular malformations is not an isolated feature but is relatively frequent. Levels of D-dimer correlate with PASP in these patients.
Autores: Redondo, P. ; Aguado-Gil, L; Páramo, José Antonio;
Revista: BRITISH JOURNAL OF DERMATOLOGY
ISSN 0007-0963  Vol. 162  2010  págs. 1156

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