Nuestros investigadores

Irene Aquerreta González

Publicaciones científicas más recientes (desde 2010)

Autores: Leyre Leache Alegria; Aquerreta, Irene; Libe Moraza; et al.
Revista: AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
ISSN 1695-0674  Vol. 73  Nº 22  2016  págs. 1840-1843
A 52-year-old man developed tinnitus and hearing loss after receiving high doses of oral morphine sulfate. His hearing loss did not fully resolve after the discontinuation of morphine, and he required the use of hearing aids.
Autores: Leache, Leire; Aquerreta, Irene; et al.
Revista: FARMACIA HOSPITALARIA
ISSN 1130-6343  Vol. 39  Nº 6  2015  págs. 320 - 332
Objective: to determine the incidence of linezolid-induced haematological toxicity and study the influence of renal clearance on its appearance and the preventive effect of pyridoxine. Methods: a retrospective observational study was conducted. Every patient treated with linezolid in a university hospital during 6 months was included. Haematological toxicity was defined as a decrease of 25% in hemoglobin, of 25% in platelets and/or 50% in neutrophils from baseline. The incidence of haematological toxicity and the percentage decrease in analytical variables were compared in patients with and without renal failure (creatinine clearance lower than 50 mL/min), using the 30 mL/min threshold, and with or without pyridoxine; using Chi -Square and U Mann-Whitney tests, respectively. Results: thirty-eight patients were evaluated. Sixteen (42%) presented haematological toxicity (2 due to a decrease in haemoglobin, 9 in platelets and 8 in neutrophils). Two patients (5%) discontinued treatment due to thrombocytopenia. Toxicity incidence was similar in patients with and without renal failure, 42% vs 42%, p = 0.970, with more or less than 30 ml/min, 67% vs 40%, p = 0.369, or with or without pyridoxine, 47.8% vs 33%, p = 0.376. Patients with renal failure had a significantly greater reduction in platelet count, p = 0.0185. Conclusion: forty-two percent of patients had haematological toxicity, being more frequent platelets and neutrophils reduction. This was not significantly higher in patients with renal failure or in those without pyridoxine. Greater reduction in platelet count was observed in patients with renal failure.
Autores: Lucena, Juan Felipe; Alegre, Félix; Rodil, Raquel; et al.
Revista: JOURNAL OF HOSPITAL MEDICINE
ISSN 1553-5592  Vol. 7  Nº 5  2012  págs. 411-415
An ImCU led by hospitalists showed encouraging results regarding patient survival and SAPS II is an useful tool for prognostic evaluation in this population. Intermediate care serves as an expansion of role for hospitalists; and clinicians, trainees and patients may benefit from co-management and teaching opportunities at this unique level of care.
Autores: Lucena, Juan Felipe; Alegre, Félix; Rodil, Raquel; et al.
Revista: JOURNAL OF HOSPITAL MEDICINE
ISSN 1553-5592  Vol. 7  Nº 5  2012  págs. 411-415
An ImCU led by hospitalists showed encouraging results regarding patient survival and SAPS II is an useful tool for prognostic evaluation in this population. Intermediate care serves as an expansion of role for hospitalists; and clinicians, trainees and patients may benefit from co-management and teaching opportunities at this unique level of care.
Autores: Aquerreta, Irene; Yuste, JR;
Libro:  Guía para la profilaxis y tratamiento de las infecciones y política antibiótica. 2ª ed
2015  págs. 42-78
Autores: Yuste, JR; Aquerreta, Irene;
Libro:  Guía para la profilaxis y tratamiento de las infecciones y política antibiótica. 2ª ed
2015  págs. 9-33
Autores: Aquerreta, Irene; Serrano-Alonso, M; Yuste, JR;
Libro:  Guía para la profilaxis y tratamiento de las infecciones y política antibiótica.
Nº 1ª ed  2013  págs. 31-54
Autores: Yuste, JR; Aquerreta, Irene;
Libro:  Guía para la profilaxis y tratamiento de las infecciones y política antibiótica. 1ª ed
2013  págs. 7-24