Nuestros investigadores

María Aubá Guedea


Publicaciones científicas más recientes (desde 2010)

Autores: Alcázar Zambrano, Juan Luis; Pascual, M. A., ; Graupera, B., ; et al.
ISSN 0960-7692  Vol. 48  Nº 3  2016  págs. 397 - 402
Objective To assess the diagnostic performance of a three-step strategy proposed by the International Ovarian Tumor Analysis (IOTA) Group for discriminating between benign and malignant adnexal masses. Methods This was a prospective observational study, performed at two tertiary-care university hospitals, of women diagnosed with an adnexal mass on transvaginal or transabdominal ultrasound between December 2012 and December 2014. Women were scheduled for an ultrasound evaluation, which was initially performed by non-expert examiners. The examiner had to classify the mass using `simple descriptors¿ (first step) and, if not possible, using `simple rules¿ (second step). For inconclusive masses, an expert examiner classified the mass according to their subjective impression (third step). Masses were managed expectantly, with serial follow-up examinations, or surgically, according to ultrasound findings and clinical symptoms. Histology was used as the reference standard. Masses that were managed expectantly with at least 1 year of follow-up were considered as benign for analytical purposes. Women with less than 1 year of follow-up were not included in the study. Results Six hundred and sixty-six women were included (median age, 41 (range, 18¿81)¿years) of whom 514 were premenopausal and 152 were postmenopausal. Based on the three-step strategy, 362 women had surgical removal of the mass (53 malignant and 309 benign), 71 masses resolved spontaneously and 233 persisted. Four hundred and forty-eight (67.3%) of 666 masses could be classified using simple descriptors and, of the 218 that could not, 147 (67.4%) were classified using simple rules. Of the remaining 71 masses, the expert examiner classified 45 as benign, 12 as malignant and 14 as uncertain. Overall sensitivity, specificity, positive likelihood ratio and negative likelihood ratio of the three-step strategy were 94.3%, 94.9%, 18.6 and 0.06, respectively. Conclusion The IOTA three-step strategy, based on the sequential use of simple descriptors, simple rules and expert evaluation, performs well for classifying adnexal masses as benign or malignant.
Autores: Utrilla-Layna Trigo, Jesús; Alcázar Zambrano, Juan Luis; Aubá Guedea, María; et al.
ISSN 0960-7692  Vol. 45  Nº 5  2015  págs. 613-17
The addition of 2D-PDA in the differential diagnosis of an adnexal mass significantly increases specificity while sensitivity remains high; however performing subsequent 3D-PDA does not provide additional information or further improve diagnostic performance subsequent to 2D-PDA.
Autores: Aubá Guedea, María; Alcázar Zambrano, Juan Luis; Baixauli Fons, Jorge; et al.
ISSN 0937-3462  Vol. 26  Nº 7  2015  págs. 985-990
Levator avulsion is associated with lower manometric squeeze pressure (p¿=¿0.032).
Autores: Pascual Corrales, Eider; Andrada Álvarez, Patricia; Aubá Guedea, María; et al.
ISSN 1575-0922  Vol. 61  Nº 7  2014  págs.  377-381
The presence of thyroid autoimmunity in women with TSH above the recommended values at the beginning of pregnancy is not associated to development of GD. However, GD prevalence was higher in these patients as compared to the Spanish general population, suggesting the need for closer monitoring in pregnant women with TSH levels ¿ 2.5 mU/mL.
Autores: Rodríguez Díez, María Cristina; Díez Goñi, María de las Nieves; Beunza Nuin, Juan José; et al.
ISSN 1137-6627  Vol. 36  Nº 2  2013  págs. 275-280
To determine the degree of confidence of students regarding obstetric examination before and after training with simulators, and assess their satisfaction with the use of simulation as a tool for acquiring skills. METHODS:Training groups involved 10 students per lecturer. Students learned how to perform Leopold's manoeuvres and measure uterine height with a simulator. The instructor supervised each physical exam. Surveys by those students who had previously done an internship at the Department of Obstetric & Gynecology were not taken into account. RESULTS:Students' confidence in performing the procedures improved significantly (p¿0.001) after the intervention.
Autores: Alcázar Zambrano, Juan Luis; Iturra, A., ; Sedda, F., ; et al.
Revista: European Journal of Obstetrics & Gynecology and Reproductive Biology
ISSN 0301-2115  Vol. 161  Nº 1  2012  págs. 92 - 95
Off-line 3D volume analysis may be a useful method for assessing adnexal masses, showing a good agreement with real-time ultrasound and having a similar diagnostic performance.
Autores: Alcázar Zambrano, Juan Luis; Aubá Guedea, María; Olartecoechea Linaje, Begoña
ISSN 1179-1586  Vol. 5  2012  págs. 1 - 13
Three-dimensional ultrasound is an imaging technique that is being introduced into clinical practice in several medical specialties. Although this technique is unlikely to replace the two-dimensional ultrasound, its role as a diagnostic tool is being explored. In fact, in the field of gynecology there has been a steady increase in the number of papers published in the last few years. These applications include: imaging the uterus, uterine cavity, adnexa, and pelvic floor as well as reproductive medicine, such as the prediction of IVF success or ovarian hyperstimulation syndrome. The aim of this paper is to review the current status of three-dimensional ultrasound in clinical practice in gynecology.
Autores: Mínguez Milio, José Ángel; Alcázar Zambrano, Juan Luis; Aubá Guedea, María; et al.
ISSN 1476-7058  Vol. 24  Nº 10  2011  págs. 1235 - 1238
The mode of delivery does not affect survival. Cesarean section provides lower morbidity and better prognosis for neurodevelopment long-term outcome in ELBW infants.
Autores: Mínguez Milio, José Ángel; Aubá Guedea, María; Diaz Cobos, Daysi Fernanda
ISSN 0937-3462  Vol. 22  Nº 12  2011  págs. 1597 - 1599
Autores: Aubá Guedea, María; Mínguez Milio, José Ángel
Libro:  La clínica y el laboratorio
2010  págs. 253-258